Ahmed Zahoor ul Hassan

Project

Identification and characterization of resistance mechanisms to hydroxyacids and dicarboxylic acids in Corynebacterium glutamicum.

Info

Area: polyomics
Project Start: 1.10.2010
Supervisor(s): Prof. Dr. Thomas Noll, Prof. Dr. Volker Wendisch
University: Bielefeld

More

Ahmed Zahoor ul Hassan is an alumnus of the CLIB-GC. He successfully defended his thesis in December 2014 and is now a postdoctoral researcher at RWTH Aachen University.

Project overview

Corynebacterium glutamicum is an organism well-known for industrial amino-acid production. Recently there has been increased interest in engineering it as a host for new products such as diamines, alcohols, carotenoids and organic acids. Genome sequencing and availability of omics tools have played a pivotal role in making this possible.

This project aims to engineer C. glutamicum strains for production of glycolate which is an organic acid with several industrial applications.

Publications

Metabolic engineering of Corynebacterium glutamicum for glycolate production. Zahoor ul Hassan A, Otten A, Wendisch VF (2014) Journal of Biotechnology 192: 366–375.

Metabolic Engineering of Corynebacterium glutamicum for Alternative Carbon Source Utilization. Leßmeier L, Matano C, Zahoor ul Hassan A, Lindner S, Wendisch VF (In Press) In: Corynebacterium glutamicum: From Systems Biology to Biotechnological Applications. Burkovski A (Ed); Horizon Press.

Zahoor A, Lindner SN, Wendisch VF (2012) Metabolic engineering of Corynebacterium glutamicum aimed at alternative carbon sources and new products. Computational and Structural Biotechnology Journal. 3 (4): e201210004.

Documents


Project description
PDF (36.6 kb)

Ahmed´s latest poster April 2011
PDF (99.8 kb)