Dr. Stefan Weidner

University

Bielefeld

department: CeBiTec, Institute for Genome Research and Systems Biology (IGS)

More

CeBiTec: Institute for Genome Research and Systems Biology (IGS), Genome Research of Industrial Microorganisms Group/Rhizobia

Research interests

Sinorhizobium meliloti is a bacterium that is found both free-living in soil and as nitrogen-fixing endosymbiont inside root-nodules of leguminous plants of the genera Medicago, Melilotus and Trigonella. S. meliloti is the object of scientific studies since decades and is considered as a model organism for bacteria-plant interaction.

A crucial scientific breakthrough was achieved with the establishment of the complete genomic sequence of S. meliloti in the framework of the international MELILO consortium. In this enterprise we sequenced the 1.68 megabases sized replicon megaplasmid pSymB and a part of the chromosome. Further details about the genome sequencing project can be found on the RhizoGATE page.

Our group is especially engaged in the stress response of S. meliloti. As symbiotic bacteria rhizobia are exposed to different environmental conditions and nutrition circumstances in the soil and inside the root nodule. We analyse particularly the regulatory influence of stress factors like pH, iron and nutrient deficiencies. As tools mainly genome-wide gene expression analysis based on microarrays and the analysis of regulator mutants are applied.

To find out more, visit the website of the Genome Research of Industrial Microorganisms Group/Rhizobia.

Students (co-)supervised

none at the moment