Dr. Lothar Eggeling

University

Duesseldorf

department: FZ Juelich, Institute of Bio- and Geosciences: Biotechnology (IBG-1)

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FZ Juelich, Institute of Bio- and Geosciences: Biotechnology (IBG-1), Systemic Microbiology, Amino Acids and Cell Wall Group

Research Interests

Worldwide more then 1.7 × 106 tonnes of amino acids are produced annually, mostly used as feed and food additives. L-glutamate and L-lysine, which represent the major production volume, are produced exclusively with the apathogenic Corynebacterium glutamicum. Our work is focused on the quantification and improvement of the cellular fluxes necessary for overproduction of metabolites. This is done by molecular and physiological means and carried out in close connection with industrial and international collaborations. Current research activities concentrate on L-lysine, L-isoleucine, and L-serine oversynthesis by C. glutamicum, as well as the characterization of lipid and arabinogalactan synthesis in C. glutamicum whose cell wall resembles in many respects that of Mycobacterium tuberculosis.

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Students (co-)supervised

Kristina Hoffmann