Friederike Degenhardt


Functional characterization of C-prenylating enzymes


Area: expression
Project Start: 23.10.2013
Supervisor(s): Prof. Dr. Oliver Kayser
University: Dortmund


Friederike’s project

Heterologous production of CBGA

Cannabigerolic acid (CBGA) displays the substrate for the synthesis of THCA, the precursor of Delta9-THC. Delta9-tetrahydrocannabinol is the main pharmacologically active compound of Cannabis sativa and is used for the treatment of a variety of diseases and symptoms.

The use of a microbial host for the biosynthesis of CBGA offers in a first step the possibility to circumvent legal issues regarding to the extraction of THCA from plants.


PDF (102.6 kb)