Friederike Degenhardt

Project

Functional characterization of C-prenylating enzymes

Info

Area: expression
Project Start: 23.10.2013
Supervisor(s): Prof. Dr. Oliver Kayser
University: Dortmund

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Friederike’s project

Heterologous production of CBGA

Cannabigerolic acid (CBGA) displays the substrate for the synthesis of THCA, the precursor of Delta9-THC. Delta9-tetrahydrocannabinol is the main pharmacologically active compound of Cannabis sativa and is used for the treatment of a variety of diseases and symptoms.

The use of a microbial host for the biosynthesis of CBGA offers in a first step the possibility to circumvent legal issues regarding to the extraction of THCA from plants.

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