Katharina Pfeifer-Sancar

Project

Transcriptome sequencing for analyzing the regulatory networks of the industrial amino acid producer Corynebacterium glutamicum

Info

Area: polyomics
Project Start: 1.12.2009
Supervisor(s): Dr. Jörn Kalinowski, Prof. Dr. Alfred Pühler
University: Bielefeld

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Katharina was an associate student of the CLIB-Graduate Cluster. She defended her thesis in February 2014 and now works for a multinational diagnostics company in NRW.

Project overview

The aim of this project is to develop transcriptome sequencing by using the transcriptome of Corynebacterium glutamicum, an industrial producer of amino acids. The obtained data led to the definition of operon structures, correction of gene starts, fine mapping of transcript starts and ends, discovery of new genes, small non-coding and cis-antisense RNAs. Thus, transcriptomic information can be used to improve the genome annotation and moreover, to characterize regulatory mechanisms in a genome-wide manner.

Transcriptome sequencing for analyzing regulatory networks of the industrial amino acid producer Corynebacterium glutamicum.

Documents


Katharina´s project
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Katharina´s latest poster April 2011
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