Kyle Lauersen

Project

Systematic optimization of microalgae cultivation for applications in (bio-) industry

Info

Area: polyomics
Project Start: 1.06.2011
Supervisor(s): Prof. Dr. Olaf Kruse, Prof. Dr. Volker Wendisch
University: Bielefeld

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Kyle defended his thesis in January 2015 and is now a postdoctoral fellow at Bielefeld University.

Project overview

Microalgae hold potentials for industrial bio-energy generation. The generation of powerful cultivation strategies for high biomass yields require enhanced culture engineering to meet market demands. Sustainable, energy positive cultivation systems, such as the outdoor photobioreactors, suffer from reduced productivity related to environmental factors. The goal of this PhD project is to use genetic engineering to systematically optimize microalgae to exhibit robust growth in sustainable outdoor photobioreactor concepts.

Systematic optimization of microalgae cultivation for applications in (bio-) industry.

Publications

Efficient recombinant protein production and secretion from nuclear transgenes in Clamydomonas reinhardtii. Lauersen K. J., Berger H., Mussgnug J. H., Kruse O. J Biotechnol 2013;167(2):101-10

Ice recrystallization inhibition mediated by a nuclear-expressed and –secreted recombinant ice-binding protein in the microalga Clamydomonas reinhardtii. Lauersen K. J., Vanderveer T. L., Berger H., Kaluza I., Mussgnug J. H., Walker V. K. Kruse O. Appl Microbiol Biotechnol 2013; 97(22):9763-72

Lauersen, K. J., Berger, H. Mussgnug, J. H. and O. Kruse. 2012. Efficient recombinant protein production and secretion from nuclear transgenes in Chlamydomonas reinhardtii. Journal of Biotechnology. Epub ahead of print.

Targeted expression of nuclear transgenes in Chlamydomonas reinhardtii with a versatile, modular vector toolkit. Lauersen, K.J., Kruse, O. and J.H. Mussgn.ug. Applied Microbiology and Biotechnology. Online Jan 15, 2015. doi:10.1007/s00253-014-6354-7 (Accepted 22.12.14)

Patent applications

Lauersen, K.J., Mussgnug, J.H., and O. Kruse. Expression vector for a secretion and detection system. European Patent Application No. EP12005108.1.

Document


Kyle’s Project
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