Claudia Holec


Monooxygenases in natural product synthesis


Area: biocatalysis
Project Start: 1.04.2013
Supervisor(s): Prof. Dr. Jörg Pietruszka
University: Duesseldorf


Project overview

In the last decades, enzymes established themselves as an interesting alternative to conventional catalysts in organic syntheses. They can catalyze regio- and stereoselective transformations, which are often challenging for conventional chemistry. The aim of the current project is the integration of biocatalytic steps in the retrosynthetic analysis of natural products. The project focuses on the enzyme family of cytochrome P450 monooxygenases and their capacity for preparative scale applications in organic synthesis.

Claudia has received several poster awards:

09/2014 Poster award, 19th ORCHEM 2014, Weimar

07/2014 Winterfeldt-Prize 2014 - third place, GDCh-JCF, Hannover

02/2014 Poster award, 26. Irseer Naturstofftage, Irsee


Claudia’s project
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