Andreas Domröse

Project

Functional expression of clustered genes encoding biosynthetic pathways

Info

Area: expression
Project Start: 1.05.2013
Supervisor(s): Prof. Dr. Karl-Erich Jaeger, Dr. Thomas Drepper
University: Duesseldorf

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Project overview

In order to gain access to high value compounds, whose biosynthetic pathways are encoded by clustered genes, we have developed the TREX (transfer and expression) system. TREX is a synthetic biology tool that enables the transfer, randomized genome integration and bidirectional expression of complex gene clusters in a broad range of bacterial hosts. Within this project, TREX will be applied to construct different Pseudomonas putida production strains for high level synthesis of prodigiosin.

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Andreas’ project
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