Jennifer Becker-Strugholz

Project

Functional genomics of cultured mammalian cells: from next-generation sequencing to cellular phenotypes

Info

Area: polyomics
Project Start: 1.10.2009
Supervisor(s): Prof. Dr. Thomas Noll, apl. Prof. Dr. Andreas Tauch
University: Bielefeld

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Alumna

Jennifer defended her thesis in Feb 2014 and now works for a company in the pharmaceutical sector.

Project overview

Today, Chinese hamster ovary (CHO) cells are at their height of technological prominence. Contrary to the increasing importance in biotechnology and industry, comprehensive transcriptome informations are still rare. In this PhD project, 454 sequencing and Illumina sequencing were used to generate long reads as well as high sequence coverage. Fallowing data assembly, coding sequence prediction is performed generating a dataset for microarray design. A customized CHO microarray will improve transcriptome analysis.

Functional genomics of cultured mammalian cells: from next-generation sequencing to cellular phenotypes

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Jennifer’s project
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